hHeart Chimera Zebrafish group
We aim to develop cardiac humanized zebrafish, which can be valuable tools
for drug testing and cell transplantation. Currently, we’re performing
experiments in which cardiac lineage cells derived from human pluripotent
stem cells (hPSCs) are xenografted into zebrafish embryos.
Microfluidics Embryo on a chip group
Microfluidic devices are attracting attention from the viewpoint of animal
welfare and because they can perform more accurate cell experiments. Our
ultimate goal is to elucidate human embryonic development using this device.
Currently, we are developing new microfluidic devices and performing differentiation
induction experiments with devices using PDMS.
Embryonic Selforganization group
The goal of the Self-Assembly Group is to elucidate the mechanisms of human
development using human iPS cells, which have the same characteristics
as human embryos.
We are currently using fluorescently labeled cells to track and quantify
cell movements in controlled culture systems.
Planarian Whole body reconstruction group
Our final goal is to mimic human embryos using neoblasts with planarian
differentiation pluripotency and to elucidate the details of human embryonic
development.
Currently, we are approaching the stable growth and culture of neoblasts
by conducting a large-scale screening of small molecular compounds to comprehensively
search for growth factors.