Stem Cell Technology

Our student participated in 10th STI-Gigaku 2025 and presented a poster on their current research.

STI-Gigaku is an international conference centered on the Sustainable Development Goals (SDGs), organized by students of Nagaoka University of Technology since 2016. The conference brings together universities and companies from Japan and around the world to discuss global challenges such as energy, climate change, and poverty, with the aim of raising awareness and driving action towards the SDGs.

The poster was highly evaluated, and the student received an award for the presentation.
Through the event, the student engaged in active discussions with researchers and students from various fields and gained valuable feedback and insights.
This achievement represents an important milestone and will further motivate our research activities.

Sunamura attended ZMDD2025: The 11th Zebrafish & Medaka Drug Discovery Meeting and presented a poster. The meeting offered an excellent platform to exchange ideas with experts in fish-based drug discovery technologies and learn about the latest advances in disease modeling and compound screening. The experience strengthened research perspectives and potential collaborative opportunities.

ZMDD focuses on drug discovery and disease modeling using zebrafish and medaka. The meeting brings together academic and industry researchers working on toxicology, pharmacology, imaging technologies, genetic engineering, and compound screening using small fish models.

Takusari participated in the 52nd Chemical and Micro-Nano Systems Society Meeting (CHEMINAS 52) and presented a poster showcasing ongoing research. Through active discussions with researchers and engineers from diverse fields, Takusari gained valuable insights into advanced micro-nano technologies and their applications in life science research. This experience will contribute significantly to future experimental development.

The Chemical and Micro-Nano Systems Society promotes interdisciplinary research integrating chemistry, life sciences, medical engineering, and micro/nano-fabrication technologies. The 52nd meeting featured presentations on microreactor systems, microfluidics, analytical and diagnostic platforms, and micro-nano engineering for biological applications.

Nuttacrit Limjantong participated in the 38th Annual Meeting of the Japanese Society for Alternatives to Animal Experiments and each delivered a poster presentation. They engaged in productive discussions with specialists working on ethical and advanced experimental platforms, gaining valuable feedback that will further enhance the quality of their research.

The Japanese Society for Alternatives to Animal Experiments promotes ethical and scientifically robust research methodologies aligned with the 3Rs (Replacement, Reduction, Refinement). The 38th annual meeting gathered researchers developing innovative non-animal testing systems, including in vitro models, computational approaches, and microphysiological systems.

Onozuka participated in the 65th Niigata Biochemistry Forum and presented a poster on current research activities. The forum provided an excellent opportunity to interact with local biochemists and students, fostering scientific communication skills and strengthening regional research networks.

The Niigata Biochemistry Forum provides a regional platform for biochemists to exchange research results and promote collaboration across institutions in the Niigata area. The forum features poster presentations and lectures spanning diverse areas of biochemistry.

Onozuka and Oda participated in the 97th Annual Meeting of the Japanese Tissue Culture Society and presented posters summarizing their recent findings. They received valuable feedback from experts in tissue culture and biomedical engineering, contributing to the refinement of their research methods and future scientific progress.

The Japanese Tissue Culture Society promotes advances in cell and tissue culture techniques that support biomedical research, regenerative medicine, and drug development. The 97th meeting highlighted cutting-edge technologies in cell culture, imaging, and in vitro modeling.

On July 7th, we hosted a welcome party for exchange students from Chulalongkorn University, one of Thailand’s most prestigious universities. As part of the cultural experience, we introduced them to a unique and fun Japanese summer tradition — Nagashi Somen (flowing noodles)!

 

It was a joyful event not just for the Thai students, but also for the Japanese students who joined in. Despite language and cultural differences, everyone connected naturally, and the atmosphere was filled with smiles and laughter.

 

Events like this remind us of the power of cultural exchange, and we hope to continue building friendships that go beyond borders.

We are delighted to share that our team participated in the The 37th Annual Meeting of the Japanese Society for Alternatives to Animal Experiments, held from Nov 29 to Dec 1 in Utsunomiya, Tochigi. The aim of this conference was to promote and disseminate the 3Rs (Reduction: reduction of the number of animals, Refinement: reduction of suffering of animals, Replacement: substitution of methods with alternatives that do not use animals), which are international principles for appropriate animal experimentation practices, and active discussions were held from various perspectives including research institutions, universities and companies.

During the conference, Jo Onozuka presented his research/work. The feedback and discussions we received were highly valuable and inspiring.

We are delighted to share that our team participated in the Cheminas 50, held from Nov 25 to 28 in Sendai, Miyagi. The conference aims to pioneer new academic and technological fields and create new industries that apply them by integrating academic disciplines that focus on materials and life phenomena, such as chemistry, life sciences, and medicine, with engineering technologies that focus on micro- and nano-scale materials, processing, measurement, control, and system construction.

During the conference, Taira Oda presented his research/work. The feedback and discussions we received were highly valuable and inspiring.

We are delighted to share that our team participated in the Zebrafish & Medaka - Based Drug Discovery Society 2024, held from Nov 18 to 19 in Rakuno Gakuen University in Ebetsu, Hokkaido. The conference featured creative discussions on the current status and challenges of disease modeling, drug discovery research, and toxicity testing using small fish from the perspectives of industry, government agencies, and academia, respectively.

During the conference, Riko Taira presented her research/work. The feedback and discussions we received were highly valuable and inspiring.

We are delighted to share that our team participated in the 10th Kanto-Ban'etsu Forum on Chemical Technology and Bioengineering, held on Nov 17th. The purpose of this conference is to promote mutual exchange among research institutes, higher education institutions (Kosen, Universities, etc.), and companies located in the Kanto-ban-Etsu area, as well as to exchange information on chemical technology.

During the conference, Keita Nakajima, Shota Tsuji and Yuto Takahashi presented their research/work. The feedback and discussions we received were highly valuable and inspiring

On Thursday, November 7, 2024, a student of our laboratory made a presentation at the 9th STI-Gigaku 2024 held at Aore Nagaoka, Nagaoka, Japan.

Shota Tsuji "Development of a new micro-contact printing method using a cutting machine"

Yuto Takahashi "Heterocellular Adhesion System by Zebrafish-Human Chimeric Proteins for Heart Regeneration"

Haruka Kato "Synthesis and characterization of near-IR absorbing d8 transition metal complexes with o-phenylenediamine derivatives for photodynamic therapy"

Taira Oda "Development of microfluidic devices using polystyrene"

Haruka Sunamura "Induction and characterization ofcardiomyocytes derived fromfluorescent reporter human iPS cells"

Jo Onozuka "Synchronization and integration of human cardiomyocytes xenotransplanted into zebrafish"

Hazuki Tsuboi "Mimicking dynamics of human gastrulation: microprint culture of human iPS cells"

Keita Nakajima "Preparation of Organogels Using Biomass Pectin for Application in Lipid-Soluble Drug Delivery Systems"

In addition, Jo Onozuka's “Synchronization and integration of human cardiomyocytes xenotransplanted into zebrafish” received the "Best Research Presentation Award by Sumitomo Riko Company Limited".

Congratulations!

STI-Gigaku is an international conference centered on the Sustainable Development Goals (SDGs), organized by students of Nagaoka University of Technology since 2016. The conference brings together universities and companies from Japan and around the world to discuss global challenges such as energy, climate change, and poverty, with the aim of raising awareness and driving action towards the SDGs.

Takahashi from Gunma Kosen has joined Ohnuma-Lab.

He will work with us from September to February as a NUT and Gunma Kosen reciprocal agreement program student.

As a member of the Zebrafish group, he will study humanization of zebrafish.

We're looking forward to working with you over the next half year!

 

Kosen students have come to open house.

Open House will be held for a week from 9/2 (Mon.) to 9/6 (Fri.).

Two Kosen students will visit our lab and experience experiments of the zebrafish group and the selforganization group.

At the end of the week, they will present what they did during the week.

On July 24th, we held a welcome and farewell party for Thai students.

We enoyed eating sushi,fried chicken, takoyaki,etc!

On June 27th and 28th, at the 96th annual meeting of the Japanese Tissue Culture Association, first-year Master's student Miyu Mori received the English Presentation Award.

Congratulations on your achievement！

Two students from Thailand came to our lab!
Their names are Pasihn Nimmanpipak and Pawaratee Pinprapharkorn.
They will participate in the lab activities from June 6 to July 31.
We will make many good memories with them!

Keita Nakajima's paper "Utilization of Multi-Ionic Interaction of Yumoto Hot Springs for Enhancing the Moisturizing Properties of Hyaluronic Acid Sodium Salt." has been accepted by Polysaccharides.

Furthermore, Miyu Mori's paper "Generation of human induced pluripotent stem cell lines derived from four Rett syndrome patients with MECP2 mutations." has been accepted by Stem Cell Research.

A party was held to celebrate their achievements.

Congratulations!

The papers can be accessed at the following links.

Keita Nakajima, Tu Minh Tran Vo, and Nur Adlin. "Utilization of Multi-Ionic Interaction of Yumoto Hot Springs for Enhancing the Moisturizing Properties of Hyaluronic Acid Sodium Salt. " Polysaccharides 5.2 (2024): 100-111. https://www.mdpi.com/2673-4176/5/2/8

Miyu Mori, et al. "Generation of human induced pluripotent stem cell lines derived from four Rett syndrome patients with MECP2 mutations. " Stem Cell Research 77 (2024): 103432. https://www.sciencedirect.com/science/article/pii/S1873506124001302

New members has joined our lab: Keita Nakajima (Docter 1st), Raul Emilio Macias Estrada (Master 1st) and Shota tsuji (Bachelor 3rd).

On February 9th and 26th, long-term internship report meetings were held, during which fourth-year undergraduate students (Mori, Sunamura, Onozuka, and Oda) who returned from their long-term internships gave presentations on what they had learned.

We have a new addition to our lab!

His name is "Goma-chan".

Please take care of "Goma-chan" from now on.

We had a Christmas party on December 27th, and everyone enjoyed eating cake together.

Limjanthong N. (D3) presented his work on "Gravity-driven microfluidics assisted with a slow-tilting table" at Cheminas 48.

https://micro-nano.chips.jp/48/

We accept a student from Danang Univ Tech as a Sakura Science Program from 6th to 22th Nov 2023.

https://ssp.jst.go.jp/en/

On 11 (Mon) Sept 2023, we had a farewell party for Takahi, who will take PhD in this September.

We would like to thank her for her guidance.
Thank you for your hard work over the past seven and a half years.

We all wish her continued success in her future endeavors.

The second Open House was held for a week from 9/4 (Mon.) to 9/8 (Fri.).

This time, three Kosen students experienced experiments with zebrafish, planaria, and selforganization group.

At the end of the week, they presented what they had done during the week and produced posters to introduce what regeneration is.

Open House was held for a week from 8/28 (Mon.) to 9/1 (Fri.).

Three Kosen students visited our lab and experienced experiments conducted by the zebrafish, planaria, and microdevice groups.

At the end of the week, they presented what they had done during the week and made posters to introduce planaria.

 

We started a homepage.

Please look forward to the update.